DeCS Server - List Exact Term

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DeCS

Descriptor English:

Factor XII

Descriptor Spanish:

Factor XII

Descriptor Portuguese:

Fator XII

Synonyms English:

Coagulation Factor XII
Factor 12
Factor Twelve
Hageman Factor

Tree Number:

Definition English:

Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.

Entry Combination - descr/qualif English:

See Related English:

History Note English:

66(64)

Allowable Qualifiers English:

Record Number:

22175

Unique Identifier:

D005174

Similar:

DeCS